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相关概念视频

Cross-bridge Cycle01:26

Cross-bridge Cycle

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As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
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Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Lateralization01:28

Lateralization

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Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
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Long-term Potentiation01:35

Long-term Potentiation

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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相关实验视频

Updated: Jul 18, 2025

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
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ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

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主要侧面硬化症 主要侧面硬化症

Sina Marzoughi1, Gerald Pfeffer2, Neil Cashman1

  • 1Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Handbook of clinical neurology
|August 24, 2023
PubMed
概括
此摘要是机器生成的。

初级侧面硬化症 (PLS) 是一种罕见的神经退行性疾病,影响上部运动神经元,原因不明. 目前的治疗方法是有症状的,这凸显了对其遗传学和病理生理学的进一步研究的需要.

科学领域:

  • 神经学 神经学
  • 神经科学是一个神经科学.

背景情况:

  • 主要侧面硬化症 (PLS) 是一种罕见的,零星的神经退行性疾病,影响上部运动神经元.
  • 它的特点是运动神经元的逐渐丧失,导致功能逐渐下降.
关键词:
下部运动神经元的运动神经元运动神经元疾病 运动神经元疾病主要侧面硬化症 主要侧面硬化症的情况是Spasticity.上部运动神经元神经元

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A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
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Last Updated: Jul 18, 2025

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
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ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

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结论:

  • 目前对PLS的治疗主要是症状性的.
  • 未来的研究方向对于理解PLS和开发有效疗法至关重要.