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通过光学连贯性断层扫描测量的周周血管密度的比较,通过光学连贯性断层扫描测量各种类型的开角玻璃眼瘤之间的血管图谱

M Simsek¹, Y Oral², S Inan²

¹Department of Ophthalmology, Mugla Education and Training Hospital, Kötekli, Marmaris Yolu No. 48, 48000 Menteşe/Muğla, Turkey.

Journal francais d'ophtalmologie

|August 24, 2023

概括

与初级开角玻璃眼 (POAG) 和健康个体相比,伪皮玻璃眼 (PXG) 和色素玻璃眼 (PG) 患者的周周血管血管密度显著降低. 这表明PXG和PG的光盘周围血流受损.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
玻璃眼研究研究玻璃眼研究

背景情况:

玻璃眼是导致不可逆转失明的主要原因.
开放角光眼包括几个亚型,包括初级开放角光眼 (POAG),伪皮光眼 (PXG) 和色素光眼 (PG).
周 papillary 血管密度是一个潜在的生物标志物,用于青光眼的进展.

研究的目的:

为了比较POAG,PXG和PG患者与健康对照者的周周血管密度.
使用光学连贯断层扫描血管学 (OCTA) 进行精确的血管密度测量.

主要方法:

一项涉及27只用POAG,34只用PXG,20只用PG,30只健康对照眼睛的横截面研究.
OCTA用于测量辐射外皮毛细血管网络中的血管密度,包括平均图像密度 (AI-DD),磁盘内密度 (ID-DD) 和外皮毛细血管密度 (PP-DD).
使用克鲁斯卡尔-瓦利斯和后期测试进行了统计分析.

主要成果:

与健康患者和POAG患者相比,PXG和PG患者的AI-DD,ID-DD和PP-DD显著降低 (P<0.001).
在PXG和PG组之间没有发现血管密度的显著差异.
在健康对照组和POAG组之间没有发现显著差异.

结论:

在PXG和PG中辐射周毛细血管密度的降低表明光盘周围的血液流动受到损害.
这些发现突出了开角格劳科马亚型之间病理生理学的潜在差异.
OCTA是评估青光眼中微血管变化的宝贵工具.

关键词:

血管的密度血管的密度血管的密度血管的密度青光眼的颜料是什么青光眼的颜料青光眼的伪皮,是一种伪皮.八国合作组织 (OCTA)颜料性玻璃眼 (pigmentary glaucoma) 是一种颜料性玻璃眼.伪皮性玻璃眼 (pseudoexfoliative glaucoma) 是一种可怕的疾病.辐射周血管密度辐射周血管密度

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