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Updated: Jul 18, 2025

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
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17β-hydroxysteroid脱酶13的脂质滴定位的结构基础

Shenping Liu1, Ruth F Sommese2, Nicole L Nedoma3

  • 1Medicine Design, Pfizer Inc, Groton, CT, 06340, USA. Shenping.Liu@pfizer.com.

Nature communications
|August 24, 2023
PubMed
概括

在Hydroxysteroid 17-beta-dehydrogenase 13 (HSD17B13) 中功能变异的丧失可能会防止肝病的进展. 晶体结构揭示了对HSD17B13功能和用于治疗肝病的抑制剂设计的见解.

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