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Updated: Jul 18, 2025

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免疫应激抑制了白血病前体前体B细胞中的先天免疫信号,从而在易患白血病的小鼠中引起白血病

Marta Isidro-Hernández1,2, Ana Casado-García1,2, Ninad Oak3

  • 1Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.

Nature communications
|August 24, 2023
PubMed
概括

天生的免疫失调驱动儿童B细胞急性淋巴细胞白血病 (B-ALL) 的发展. 在白血病前的细胞中,Myd88的下调加速了B-ALL,而Toll-like受体3的信号延迟了它.

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Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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