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针对不同免疫区的免疫疗法与放射治疗相结合,诱导了耐药瘤的回归

Nils-Petter Rudqvist1,2,3, Maud Charpentier1, Claire Lhuillier1,4

  • 1Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, 10065, USA.

Nature communications
|August 24, 2023
PubMed
概括

放射治疗与CTLA-4抑制相结合,通过改变T细胞种群,改善抗癌免疫力. 这种组合疗法,特别是与CD40激动剂,显示了增强瘤反应在耐药癌症的承诺.

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