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Updated: Jul 18, 2025

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在胰腺癌中,DDX18通过转录激活的STAT1表达驱动瘤免疫逃生

Guoying Dong1, Qin Wang2, Mingxin Wen1

  • 1Department of Anatomy, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.

Oncogene
|August 24, 2023
PubMed
概括

胰腺癌 (PDAC) 显示出明显的染色质变化,DDX18 (DEAD-box RNA helicase 18) 的上调与生存率差相关. 抑制DDX18-STAT1通路为PDAC提供了一个新的治疗策略.

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