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Updated: Jul 18, 2025

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在Okazaki成熟过程中进行四点分子交换

Margherita M Botto1,2, Alessandro Borsellini1,3, Meindert H Lamers4

  • 1Department of Cell and Chemical Biology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

Nature structural & molecular biology
|August 24, 2023
PubMed
概括

DNA复制需要精确的酶协调,以从滞后链中去除RNA原始酶. 这项研究揭示了四步分子移交机制,确保了高效的原料去除和DNA合成完成在大肠杆菌中.

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