瘦身量与青少年异常学脊椎病之间的关联:一个元分析
Wei Xu1, Jiajie Zang2, Fan Wu3
1School of Public Health, Shanghai Jiao Tong University, Shanghai, 200025, China.
BMC musculoskeletal disorders
|August 24, 2023
概括
与对照人群相比,青少年异常学脊椎病 (AIS) 与患者的瘦肉量较低有关. 这一发现表明瘦身量可能在AIS发展中发挥作用,但需要进一步的研究来确认.
科学领域:
- 整形外科 整形外科 整形外科
- 生物统计学 生物统计学
- 人体生理学 人体生理学
背景情况:
- 青少年异常学脊椎病 (AIS) 是一种复杂的脊椎形.
- 身体构成,特别是肌肉质量在AIS病变发生过程中的作用仍然不清楚.
- 了解有助于AIS的因素对于开发有效的干预措施至关重要.
研究的目的:
- 进行一项元分析,评估瘦肉质与青少年异常学脊椎病 (AIS) 之间的关联.
- 综合现有研究的证据,以确定AIS患者和健康对照人群之间的瘦身量是否有所不同.
主要方法:
- 在多个英语和中文数据库 (CENTRAL,MEDLINE,EMBASE,PubMed,Web of Science,CBM,CNKI,VIP,WANGFANG DATA) 进行了系统的搜索.
- 包括的研究是病例控制和横截面设计.
- 数据由两位作者独立提取,并使用Stata 15.0.0进行分析.
主要成果:
- 包括8项研究,包括1771例AIS病例和6340例对照.
- 分析显示,与对照组相比,AIS组的瘦肉量显著下降 (MD = -1.95,95% CI [-2.96, -0.93]).
- 亚组分析表明,女性AIS患者的肌肉量较低,成人研究和亚洲人群的差异更大.
结论:
- 这些发现表明,较低的肌肉质量和青少年异常学脊椎病 (AIS) 之间存在显著的关联.
- 瘦肉质可能与AIS的发病有关.
- 由于包含的研究数量有限,需要进一步的高质量研究来验证这些结论.
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