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Updated: Jul 18, 2025

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系统性红斑狼与心脏病的风险有关:孟德尔的随机化研究

Qiaolin Wang1,2, Sujie Jia3, Qianjin Lu1,2

  • 1Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.

Autoimmunity
|August 25, 2023
PubMed
概括

系统性红斑狼 (SLE) 显著增加患乳病 (CeD) 的风险. 这一发现表明SLE与肠道免疫系统功能障碍之间存在联系.

关键词:
门德尔的随机化系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.患有乳性疾病的患者.

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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