在患有典型GERD症状的患者中,RDQ和GERDQ用于预测侵蚀性食道炎的比较
Titong Sugihartono1,2, Amal Arifi Hidayat3, Michael Austin Pradipta Lusida3
1Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
概括
反流性疾病问卷 (RDQ) 在识别侵蚀性食道炎方面略高于GERD问卷 (GERDQ). 印度尼西亚版本的RDQ是评估GERD症状的有效和可靠工具.
科学领域:
- 胃肠病学 胃肠病学
- 临床诊断 临床诊断 临床诊断
- 医疗保健服务研究 医疗服务研究
背景情况:
- 胃食道逆流性疾病 (GERD) 的管理因侵蚀性食道炎的存在而有所不同.
- 由于印尼上部内镜的有限可用性,需要可靠的非侵入性诊断工具.
- 本研究探讨了在印度尼西亚背景下对验证的GERD评估工具的需求.
研究的目的:
- 为了比较反流性疾病问卷 (RDQ) 和GERD问卷 (GERDQ) 在预测临床显著侵蚀性食道炎方面的表现.
- 为了确定印尼语翻译的RDQ的有效性和可靠性.
- 在资源有限的环境中为GERD管理提供临床决策信息.
主要方法:
- 92名怀疑患有GERD的成年人完成了RDQ和GERDQ.
- 使用接收器操作曲线 (ROC) 分析来评估每个问卷的诊断性能.
- 印尼的RDQ经过了翻译,文化适应和构造有效性和可靠性的评估.
主要成果:
- 在预测侵蚀性食道炎 (LA等级B或更高) 中,RDQ显示曲线下的面积 (AUC) 比GERDQ略高 (0.602对0.589).
- 确定了最佳切断点:RDQ在20 (灵敏度73%,特异性50%) 和GERDQ在8 (灵敏度77%,特异性43%).
- 印度尼西亚的RDQ显示出卓越的可靠性 (克朗巴赫的α=0.900),并证实了构造的有效性 (r > 0.205,p < 0.01).
结论:
- 与GERDQ相比,RDQ是一个稍微优越的工具,用于预测这一群体的显著侵蚀性食道炎.
- 印尼语翻译的RDQ是GERD评估的有效和可靠的工具.
- 这些发现支持在内镜有限的临床实践中使用印尼的RDQ.
相关概念视频
01:29Gastroesophageal Reflux Disease II: Clinical Features and Management
111
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
111
01:29Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
349
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
349
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
174
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
174
01:21Barrett Esophagus-II: Clinical Manifestations and Management
192
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
192
01:21Barrett Esophagus-I: Introduction
123
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
123
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
38
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
38