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静坐行为与内皮功能障碍之间的关系在中国的一项横截面研究中

Ping-Ting Yang¹, Sai-Qi Yang¹, Yong-Mei He²

¹Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.

Frontiers in cardiovascular medicine

|August 25, 2023

概括

休时间的增加与血管内皮功能障碍的风险更高有关. 减少久坐不动的习惯可能会改善一般人群的血管健康.

科学领域:

心血管健康心血管健康
血管生物学血管生物学
公共卫生公共卫生

背景情况:

久坐不动行为是众所周知的各种疾病的风险因素.
以前的研究主要集中在急性久坐行为对血管内皮功能的影响上.
关于长期久坐的生活习惯与大群体血管功能之间的关联的数据有限.

研究的目的:

调查自我报告的久坐行为与外周血管功能之间的相关性.
在中国的大型现实检查群体中评估血管内皮功能.

主要方法:

从中国的两个健康管理中心招募了13,220名参与者 (2017-2021).
通过关于生活习惯的问卷和手臂动脉流媒扩张 (FMD) 测量收集的数据.
使用多变量回归分析来确定关联.

主要成果:

确定了3,205名参与者 (24.2%) 患有内皮功能障碍 (FMD ≤5.0%).
观察到一种剂量与反应的关系:较长的休时间与血管内皮功能障碍的风险增加相关.
与每天休时间>6小时的参与者相比,与每天休时间<2小时的参与者相比,休时间静坐时间的参与者表现出明显更高的风险 (OR=1.618,P<0.001).

结论:

较长的休静坐时间与较高的血管内皮功能障碍患病率有关.
休时间的久坐行为被确定为中国检查人口中血管内皮功能障碍的重要危险因素.
研究结果强调了减少久坐时间对于保持血管健康的重要性.

关键词:

在 FMD 和 FMD 的情况下,对人口进行检查.内皮质功能障碍在内皮质功能障碍一个久坐不动的行为.工作时间工作时间

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