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相关概念视频

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Vascular Resistance

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Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
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Overview of the Vascular System01:20

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The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
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相关实验视频

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An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors
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血管参数的计算:实施方法和性能分析方法.

Mohamed Yacin Sikkandar1, Sridharan Padmanabhan2, Bobby Mohan2

  • 1Department of Medical Equipment Technology, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.

Biosensors
|August 25, 2023
PubMed
概括

一种新的超声波设备,CaNVAS,可以持续,非侵入性监测血管硬和血压. 这项创新提供了准确的心血管评估,对于管理心脏病至关重要.

关键词:
声波是一种声波.动脉的合规性 动脉合规性血压 血压 血压 血压脉冲波的速度是脉冲波的速度.硬度指数的硬度指数是什么

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A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
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A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
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科学领域:

  • 生物医学工程 生物医学工程
  • 心血管研究研究心血管研究
  • 医疗器械 医疗器械

背景情况:

  • 对脉冲波速度 (PWV),血压 (BP),动脉顺应 (AC) 和刚度指数 (SI) 等血管参数的准确体内测量对于心血管疾病评估至关重要.
  • 传统的血压测量方法 (手套式或侵入式导管) 通常不连续,需要手动计算其他参数.
  • 需要用于血管健康评估的非侵入性,持续监测解决方案.

研究的目的:

  • 展示自动化和准确的体内超声波传感器的可行性,用于持续的,非侵入性的血管参数测量.
  • 引入持续和非侵入性血管硬性和动脉合规性选器 (CaNVAS) 设备.
  • 为了验证CaNVAS设备在测量血管参数方面的准确性和可靠性.

主要方法:

  • 开发使用5MHz超声波传感器 (2.2-10MHz范围) 传输声波穿过动脉壁的CaNVAS设备.
  • 捕获反射回声并应用预处理技术来计算基于频率转移的PWV.
  • 建立CaNVAS测量的PWV和血压计获得的BP值之间的指数相关性,用于即时BP计算.

主要成果:

  • 该 CaNVAS 装置证明了测量的 PWV 和 BP 之间的指数相关性,使即时 BP 计算成为可能.
  • 对250名受试者的验证显示,血管参数测量的准确率为95%,平均变化系数为12.5%.
  • 该设备在运动前后条件下评估血管参数的可靠性和精度被证明是可靠的.

结论:

  • 该 CaNVAS 设备提供了一个可行的解决方案,用于自动,准确,连续和非侵入性的 in vivo 血管参数监测.
  • 这项技术可以在外科手术和随访期间对心血管疾病的评估和管理提供重大帮助.
  • CaNVAS提供了一种可靠和精确的工具,用于评估血管硬和动脉合规性.