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基于智能手机的刚性内镜装置,具有血液动力学反应成像和激光光斑对比成像

Youngkyu Kim¹, Woo June Choi², Jeongmin Oh³

¹Biomedical Engineering Research Center, Asan Medical Center, Seoul 05505, Republic of Korea.

|August 25, 2023

概括

这项研究引入了基于智能手机的双波长激光光斑对比成像 (LSCI) 内镜,用于实时血流和氧化监测. 该设备提供了一个有价值的平台,用于对内部器官的血管血液动力学进行治疗评估.

科学领域:

生物医学光学生物医学光学
医疗成像医学成像
临床诊断临床诊断临床诊断临床诊断

背景情况:

由于智能手机技术的进步,智能手机越来越多地集成到护理点 (POC) 设备中.
之前的工作展示了基于智能手机的手持内镜,使用激光光斑对比成像 (LSCI).

研究的目的:

开发一种多功能手持内镜,将智能手机技术与双波长LSCI相结合.
为了使动态血流和血红蛋白氧化 (HbO2,Hbr,HbT) 的同时监测.

主要方法:

开发一个智能手机集成的双波长LSCI系统.
使用智能手机快速获取数据和计算LSCI数据.
在缺血和再输液期间,用流量幻影和体内大鼠肠道模型测试设备.

主要成果:

该设备使用LSCI成功生成了血液 perfusion 地图.
在体内实验显示,血流和HbO2在缺血和高血压后的缺血期间减少.
具备实时评估血液动力学变化的能力.

结论:

智能手机组合双波长LSCI内镜是功能POC内镜的一个有前途的平台.
这项技术有助于理解内部器官中的血管血动力学.
潜在的应用包括在护理点对血管疾病的诊断和治疗监测.

关键词:

缺血的动物模型.血液动力学反应成像成像激光光斑对比成像激光光斑对比成像医疗中心的关心点智能手机的智能手机智能手机的智能手机.

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