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Updated: Jul 18, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

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Published on: January 24, 2016

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SPOP针对免疫转录因子IRF1进行蛋白质体降解

Irene Schwartz1,2, Milica Vunjak1,2, Valentina Budroni1,2

  • 1Department of Microbiology, Immunobiology and Genetics, Max Perutz Labs, University of Vienna, Vienna, Austria.

eLife
|August 25, 2023
PubMed
概括

干扰素调节因子1 (IRF1) 蛋白水平由斑点型BTB/POZ蛋白 (SPOP) 调节,以平衡免疫反应并预防自身免疫. SPOP针对IRF1的退化目标,保持最佳的IRF1水平.

关键词:
人类 人类 人类 人类 人类 人类 人类免疫学 免疫学 免疫学这是一种炎症炎症炎症炎症.干扰素调节因子1 干扰素调节因子1这里是鼠标鼠标鼠标鼠标鼠标鼠标.蛋白质酶体蛋白质组是什么蛋白质降解 蛋白质降解在任何地方都是无处不在的.

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