早期乳腺癌的地域治疗:现状和未来前景
Sayeh Lavasani1, Erin Healy2, Kari Kansal3
1Division of Hematology and Medical Oncology, UC Irvine, Orange, CA 92868, USA.
Current oncology (Toronto, Ont.)
|August 25, 2023
概括
综合手术,全身疗法和放射治疗的多学科乳腺癌治疗显著减少了局部区域的复发. 早期检测和手术技术的进步改善了患者的治疗结果和生活质量.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 辐射瘤学 辐射瘤学
背景情况:
- 乳腺癌的局部区域复发是一个重大问题.
- 涉及手术,全身疗法和辐射的多学科方法改善了结果.
- 早期检测和先进的手术技术是改善乳腺癌管理的关键.
研究的目的:
- 审查当前关于乳腺癌局部区域治疗的证据.
- 总结乳腺癌管理中的当代方法.
- 讨论地方区域乳腺癌治疗的未来方向.
主要方法:
- 对当前证据的文献综述.
- 综合了关于手术,全身和辐射疗法的数据.
- 讨论正在进行的临床试验和不断发展的技术.
主要成果:
- 改进的外科技术和新辅助疗法 (例如检查点抑制剂,双重HER2导向疗法) 增加了病理完整反应.
- 辅助放射治疗的进步提高了局部区域控制,减少了复发.
- 手术降级改善了生活质量,同时保持了低复发风险.
结论:
- 目前用于乳腺癌的局部区域治疗已经导致更好的结果和减少复发率.
- 目前正在进行的研究和技术进步旨在进一步优化治疗疗效,尽量减少毒性.
- 乳腺癌治疗的未来包括完善辐射技术和探索新的全身疗法.
相关概念视频
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K


