益生菌和便移植:延缓慢性病进展的干预措施?
Harshavardhan Sanekommu1, Sobaan Taj1, Rida Mah Noor2
1Department of Medicine, Jersey Shore University Medical Center, 1945 NJ-33, Neptune City, NJ 07753, USA.
Clinics and practice
|August 25, 2023
概括
通过准肠-轴,可以改善慢性病 (CKD) 的管理. 基于微生物群的干预措施,如益生菌,在减缓CKD进展方面表现有前途.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 胃肠病学 胃肠病学
- 微生物组研究 微生物组研究
背景情况:
- 慢性病 (CKD) 影响全球7亿人,医疗费用很高.
- 目前的CKD管理主要集中在Renin Angiotensin Aldosterone (RAS) 抑制剂和控制血压和糖尿病.
- 新出现的证据强调了肠-轴在CKD进展中的作用.
研究的目的:
- 审查目前关于对CKD基于微生物群的干预措施的证据.
- 探索益生菌,益生菌,共生菌和便微生物移植在治疗CKD方面的潜力.
- 总结未来在慢性病治疗中利用肠轴的可能性.
主要方法:
- 最近的调查和临床研究的文献综述.
- 对基于微生物群的干预措施 (益生菌,益生菌,共生菌,FMT) 的数据分析.
- 关于肠轴和CKD进展的证据综合.
主要成果:
- 肠轴的破坏显著影响CKD的进展.
- 基于微生物群的干预措施在CKD管理中显示出有希望的结果.
- 特定的干预措施,如益生菌,可能有助于延迟疾病的进展.
结论:
- 基于微生物群的疗法提供了一种新的方法来补充现有的CKD治疗方法.
- 准肠道微生物组有可能减缓CKD的进展.
- 对益生菌,益生菌,共生菌和FMT进行进一步的研究对于CKD管理是有必要的.
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