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过去,现在和未来关于移植急性损伤脏的观点
Rachana Punukollu1, Margaret Ryan2, Suman Misra3
1Division of Transplant Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA.
Clinics and practice
|August 25, 2023
概括
患有急性损伤 (AKI) 的患者的脏在移植中显示出有前途的移植功能和存活率. 采购活检和机器输液等策略改善了结果,并扩大了捐赠池的选择.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植手术 移植手术
- 器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器
背景情况:
- 急性损伤 (AKI) 脏由于感知到的不良结果而未得到充分利用.
- 对移植器官生存和功能的担忧限制了AKI捐赠器官的使用.
研究的目的:
- 审查目前和未来对使用来自急性损伤 (AKI) 捐赠者的的观点.
- 分析与AKI移植相关的结果和管理策略.
主要方法:
- 进行了一项全面的PubMed搜索,重点关注AKI的背景下脏移植.
- 关于AKI脏的过去,现在和未来的意见和数据的文献综述.
主要成果:
- 短期和长期数据表明,AKI脏的移植功能和存活率有利.
- 采购活检有助于区分伤害类型,而机器输液可以减少延迟移植功能 (DGF).
- 管理DGF涉及早期透析,优化免疫抑制和门诊透析策略.
结论:
- 尽管有积极的结果,但AKI脏利用的障碍仍然存在.
- 采购活检,机器输液和期待的DGF管理是成功的策略.
- 增加经验和改进AKI脏的利用,可以扩大捐献器官库.
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