COVID-19疫苗和辅助生殖技术:系统审查
Elena Satorres-Pérez1, Alicia Martínez-Varea1, José Morales-Roselló1
1Department of Obstetrics and Gynaecology, La Fe University and Polytechnic Hospital, Avenida Fernando Abril Martorell 106, 46026 Valencia, Spain.
Journal of personalized medicine
|August 25, 2023
概括
对于接受辅助生殖技术 (ART) 的人来说,COVID-19疫苗接种是安全的. 对24项研究的审查发现,COVID-19疫苗对生育治疗结果没有负面影响,包括怀孕率.
科学领域:
- 生殖医学 生殖医学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 辅助生殖技术 (ART) 涉及复杂的医疗干预不孕症.
- 有关COVID-19疫苗接种对ART结果的影响存在担忧.
- 了解这一群体的疫苗安全性对于患者护理至关重要.
研究的目的:
- 系统地审查和综合有关COVID-19疫苗接种和ART之间的关联的现有证据.
- 评估疫苗接种对关键生育治疗参数和怀孕结果的影响.
主要方法:
- 在主要数据库 (PubMed-Medline,Cochrane,Web of Science) 和指南中进行系统的文献搜索.
- 包括对接种ART的接种疫苗 (病例) 和未接种疫苗 (对照) 患者进行比较的初级研究.
- 收集和分析关于卵细胞刺激,胚胎质量,植入和怀孕率的数据.
主要成果:
- 审查中包括了24项研究.
- 在疫苗接种和未接种ART患者之间,在卵细胞刺激,胚胎质量,植入率或妊娠结果方面没有观察到统计学上显著的差异.
- 不同的疫苗类型和ART方法显示了可比的结果.
结论:
- 现有证据表明,COVID-19疫苗接种不会对辅助生殖技术的结果产生不利影响.
- 接受ART治疗的患者和医疗保健提供者应该通过安全数据得到放心.
- 对于正在进行生育治疗的个人,建议接种COVID-19疫苗.
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