唾液作为口腔和慢性退行性非传染性疾病的生物标志物
Michele Basilicata1,2, Massimo Pieri2,3, Giulia Marrone4
1UOSD Special Care Dentistry, Policlinico Tor Vergata, 00133 Rome, Italy.
Metabolites
|August 25, 2023
概括
唾液分析为早期疾病检测提供了一种新的方法,可能将口腔健康与慢性病 (CKD) 等系统性疾病联系起来. 调节口腔和肠道微生物群可能有助于控制这些疾病.
科学领域:
- 生物化学 生物化学
- 微生物学 微生物学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 唾液对口腔健康,消化和免疫非常重要.
- 饮食和吸烟等因素会改变唾液和口腔微生物组,增加疾病风险.
- 改变的口腔微生物组与全身性疾病有关.
研究的目的:
- 审查唾液在早期检测口腔和全身疾病,包括慢性病 (CKD) 的潜力.
- 检查口腔健康,全身疾病和肠道微生物群失调之间的相关性.
- 探索微生物群调制作为口腔疾病和CKD的辅助疗法.
主要方法:
- 文献综述侧重于唾液参数和疾病标志物.
- 分析口腔健康,全身疾病和微生物群之间的关系.
- 探索涉及益生菌,后生菌和共生菌的治疗策略.
主要成果:
- 唾液参数显示出作为早期检测口腔和全身病理的生物标志物的潜力.
- 口腔疾病和慢性病 (CKD) 之间存在强烈的相关性.
- 口腔和肠道微生物群失生症与口腔和全身疾病有关.
结论:
- 唾液分析是早期非侵入性疾病诊断的一个有前途的工具.
- 向口腔和肠道微生物群调节可能为CKD和口腔疾病提供新的治疗途径.
- 需要进一步的研究来验证唾液生物标志物和基于微生物群的疗法.
相关概念视频
Salivary Glands and Saliva
753
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
753
What is Monogastric Digestion?
71.5K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.5K
Oral Cavity
817
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
817
Assessment of the Mouth
251
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
251


