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Updated: Jul 18, 2025

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice
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Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice

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CSF-1R+巨细胞通过IL-18控制肠道微生物群增强的肝脏不变NKT功能

Chi Ma1, Justin McCallen1, John C McVey1,2

  • 1Thoracic and GI Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Journal of immunology (Baltimore, Md. : 1950)
|August 25, 2023
PubMed
概括

用万科米辛改变肠道微生物组可以提高肝脏不变天然杀手T (iNKT) 细胞的功能. 这种调节通过肠道细菌间接地影响巨细胞产生IL-18,从而增强iNKT细胞活性.

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Depletion and Reconstitution of Macrophages in Mice

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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

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相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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