在康复性COVID-19患者与过敏性鼻炎患者中,鼻紧接点的动态变化
Yating Liu1, Zaichuan Wang1, Limin Zhao1
1Departments of Otorhinolaryngology Head and Neck Surgery, and Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
International forum of allergy & rhinology
|August 25, 2023
概括
COVID-19患者显示鼻紧结功能和过敏严重程度之间存在负相关性. 欧米克朗变种可能会阻碍过敏性鼻炎 (AR) 患者鼻紧结的恢复.
科学领域:
- 免疫学 免疫学 免疫学
- 病毒学 病毒学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 过敏性鼻炎 (AR) 涉及鼻腔炎症和表皮屏障功能受损.
- 感染COVID-19可能会影响呼吸系统的完整性和免疫反应.
- 紧密的结点对于维持鼻上皮质屏障至关重要.
研究的目的:
- 调查COVID-19患者鼻紧结完整性和过敏反应之间的关系.
- 评估Omicron变异对AR患者紧接口恢复的潜在影响.
主要方法:
- 从有或没有AR的COVID-19患者的鼻样本的分析.
- 评估紧结模块分数和过敏模块分数.
- 与不同SARS-CoV-2变种感染的患者之间的结局的比较.
主要成果:
- 在COVID-19患者的鼻紧接模块得分和过敏模块得分之间观察到显著的负相关性.
- 与其他变种相比,感染Omicron变种的患者表现出较慢的紧结功能恢复.
结论:
- 在COVID-19患者中,鼻紧接口的完整性受到损害,与过敏症状相关.
- 在AR患者中,Omicron变异可能会延长鼻上皮屏障的恢复,可能会加剧过敏症状.
更多相关视频
相关概念视频
Upper Respiratory Drugs: Decongestants
263
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
Most decongestants are readily available over-the-counter in...
263
Drugs Used in Upper Respiratory Disorders: Overview
290
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
290
Nose and Nasal Cavity
2.8K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
2.8K
Asthma: Pathogenesis and Management
443
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
443
Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
342
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
342


