肠道微生物群干预措施以保持残留的功能
Denise Mafra1,2, Julie A Kemp1, Natalia A Borges3
1Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niteroi 24020-140, Brazil.
Toxins
|August 25, 2023
概括
在慢性病 (CKD) 中,保存功能至关重要. 通过饮食和其他策略调节肠道微生物群可能有助于减轻脏损伤并改善患者的治疗结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 剩余功能对于慢性病 (CKD) 患者的生活质量和预后至关重要.
- 肠道功能失调,尿素毒素和内毒素有助于CKD的损伤.
- 饮食是肠道失调的主要驱动因素,影响CKD的进展.
研究的目的:
- 审查肠道微生物群代谢对CKD残留功能 (RKF) 的作用.
- 通过调节肠道微生物群平衡来探索保护RKF的策略.
主要方法:
- 对肠道微生物群,CKD和RKF研究的文献综述.
- 对肠道微生物群调节的饮食,药物和便移植干预措施的分析.
主要成果:
- 肠道微生物群的组成显著影响CKD进展和RKF.
- 饮食干预措施在调节肠道微生物群和潜在地保护RKF方面表现有前途.
- 需要进一步的研究,以充分阐明微生物群调节对RKF的影响.
结论:
- 调节肠道微生物群是一种有前途的策略,可以在CKD患者中保存残留功能.
- 饮食干预是管理肠道失调及其脏后果的关键途径.
- 针对肠-轴为CKD管理提供了潜在的治疗益处.
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