绿地类型与精神分裂症的肠道微生物组之间的关联:所有绿地都发挥了同等作用吗?
Ning Wei1,2, Shusi Wang3, Xuanxuan Li1,2
1Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China.
Environmental science and pollution research international
|August 25, 2023
概括
绿色空间类型对精神分裂症 (SCZ) 的肠道微生物群产生影响. 树木覆盖,与草不同,积极影响肠道细菌,包括Bifidobacterium longum,可能改善SCZ健康.
科学领域:
- 环境健康 环境健康
- 微生物组研究 微生物组研究
- 心理健康研究 心理健康研究
背景情况:
- 越来越多的证据将肠道微生物组与精神分裂症 (SCZ) 联系起来.
- 绿色空间有利于心理健康,但对SCZ肠道微生物群的影响尚不清楚.
- 绿色空间类型的变化可能会对肠道微生物组成产生不同的影响.
研究的目的:
- 研究不同类型的绿色空间如何影响精神分裂症患者的肠道微生物群.
- 在SCZ患者中确定与各种绿色空间类型相关的特定肠道微生物种群.
主要方法:
- 来自243名精神分裂症患者的便样本使用16S rRNA基因测序进行了分析.
- 绿地覆盖面 (树木,草) 计算在住宅周围800米,1500米和3000米的缓冲区内.
- 为了分析关联,使用了变异的变分析 (PERMANOVA) 和线性回归.
主要成果:
- 树木覆盖,而不是草,与1500米和3000米的缓冲区的肠道微生物组成有显著的关联.
- 较高的树木覆盖率与特定类型的丰富性增加相关,特别是长长的Bifidobacterium.
- 绿色空间对SCZ肠道微生物群的影响因绿色空间类型而异.
结论:
- 绿色空间的类型在调节精神分裂症患者的肠道微生物群中发挥着独特的作用.
- 树木覆盖面似乎对这一群体中关键的肠道微生物组成具有主导作用.
- 研究结果表明,可以优化绿色空间的城市规划,以提高SCZ的心理健康.
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