对影响晚期胃癌老年患者长期生存的危险因素的分析
Seong-A Jeong1, Jeong Hwan Yook2, Moon-Won Yoo2
1Department of Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.
Aging clinical and experimental research
|August 25, 2023
概括
患有晚期胃癌的超重老年患者在胃切除术后的长期生存率有所改善. 瘤阶段,手术程度和并发症在这个人群中显著影响生存结果.
科学领域:
- 老年瘤学 老年瘤学
- 手术瘤学手术瘤学
- 胃肠道癌症研究研究
背景情况:
- 以前的研究集中在经过胃切除术的老年胃癌患者的术后并发症.
- 有限的研究存在于影响长期生存的因素在这个人口.
研究的目的:
- 确定治疗性胃切除术的晚期胃癌 (II+阶段) 的老年患者 (75岁以上) 长期生存的预测因素.
- 分析基线特征,并发症,手术/病理因素和营养状况的风险因素.
主要方法:
- 对晚期胃癌 (II+阶段) 的老年患者的回顾性分析.
- 风险因素分为基线,并发症,外科/病理和营养组.
- 使用了卡普兰-梅尔生存分析和多变量分析.
主要成果:
- 五年整体和特定疾病的存活率分别为51.5%和58.3%.
- 女性的性别和超重状况与显著更长的生存时间有关.
- 整体胃切除术,晚期瘤阶段和整体并发症是生存的独立负面预测因素.
结论:
- 超重状态,胃切除术的程度,瘤阶段和整体并发症是老年晚期胃癌患者长期生存的重要决定因素.
- 在这个群体中,外科医生应谨慎对待全胃切除术,并优先考虑营养支持和并发症管理.
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