疹病毒脑膜炎呈现为轨道肌肉炎 - 一个病例报告
Akash Gowda1,2, Jessica Y Tong1,2, Dinesh Selva1,2
1South Australian Institute of Ophthalmology, The University of Adelaide, Adelaide, Australia.
Orbit (Amsterdam, Netherlands)
|August 25, 2023
概括
疹病毒 (Varicella zoster virus,简称VZV) 引起了一种罕见的脑膜炎病例,从轨道肌炎开始,并迅速进展到无皮疹死亡. 这种VZV呈现对治疗没有反应,突出显示了非典型的神经参与.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 眼科医生 眼科 眼科
背景情况:
- 疹病毒 (Varicella zoster virus,简称VZV) 通常会导致水和带状疹.
- 脑膜大脑炎是大脑及其周围膜的严重炎症.
- 轨道肌炎和轨道顶部综合征是影响眼的炎症状况.
研究的目的:
- 报告一个独特的VZV脑膜炎病例.
- 描述一种非典型的VZV感染表现.
- 强调在无法解释的神经和轨道综合征中考虑VZV的重要性.
主要方法:
- 病例报告详细介绍了临床表现,诊断程序和治疗反应.
- 轨道活检用于VZV检测.
- 腰部穿刺用于脑脊液分析和VZV确认.
主要成果:
- 患者出现了轨道肌肉炎,迅速发展为轨道顶部综合征和脑膜炎.
- 皮疹在整个疾病期间都没有出现.
- 通过轨道活检和脑脊液分析证实了VZV感染.
- 脑膜炎对类固醇和抗病毒疗法都不耐药,导致死亡.
结论:
- VZV可以引起严重的脑膜炎,与轨道肌肉炎的不寻常的初始呈现.
- 没有皮疹并不排除VZV作为神经疾病的原因.
- 这一案例强调了在复杂的轨道和神经表现中迅速诊断和考虑VZV的必要性.
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