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Updated: Jul 18, 2025

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model
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4 - 八基伊塔可纳酸通过阻断其棕化作用来限制STING激活

Chaofei Su1, Tian Cheng1, Jian Huang1

  • 1School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology (Ministry of Education), Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.

Cell reports
|August 25, 2023
PubMed
概括

4-octyl itaconate (4-OI) 通过化STING,抑制了干扰素基因 (STING) 路径的循环氨酸单酸氨酸单酸合成酶 (cGAS) - 刺激器. 这一发现揭示了一种新的翻译后修饰,调节免疫反应.

关键词:
4-OI 的使用方法.CP: 免疫学 免疫学科普:分子生物学 分子生物学在PTM的PTM.这是一种基化.cGAS-STING 的使用情况.棕细胞代谢的发生

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