反侧的低至中等可疑结节在患有乳腺甲状腺癌的患者中,对切术不是一个禁忌
Shin Jeong Pak1, Douk Kwon1, Byung-Chang Kim1
1Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Thyroid : official journal of the American Thyroid Association
|August 25, 2023
概括
对于带有 contralateral 结节的单侧 papillary 甲状腺癌 (PTC),叶片切除术是一种安全的初始治疗方法. 大多数抵押品结节保持稳定或解决,发展为PTC的速度很低.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 甲状腺癌研究研究
背景情况:
- 对单侧乳头甲状腺癌 (PTC) 与对侧结节的最佳外科手术方法进行了讨论.
- 单边PTC患者的逆侧结节需要对其行为和对结果的影响进行仔细评估.
- 腔切除术是一种潜在的手术选择,但在这个特定的患者群体中,其长期疗效需要进一步研究.
研究的目的:
- 为了评估长期的结果 叶叶切除术 患者 单侧 papillary 甲状腺癌 (PTC) 和 contralateral 结节.
- 评估单边PTC的分叶切除术后对侧面结节的行为和进展.
- 确定带切除术作为该患者群体的初始手术策略的安全性和可行性.
主要方法:
- 回顾性队列研究包括1761名患有单边PTC的患者,这些患者接受了叶片切除术.
- 根据手术时存在或缺少逆侧结节的情况,患者被分为几组.
- 长期随访 (中位数为59个月) 包括对逆向结节大小变化和逆向PTC的发展的评估.
主要成果:
- 在存在的逆侧结节中,54.7%保持稳定,减少或消失;14.8%增加≥0.3厘米.
- 在2.9%的患有 contralateral 结节的患者中,诊断出了 contralateral papillary 甲状腺癌 (PTC).
- 反侧PTC的五年无病存活率很高 (98.2%有结节 vs 99.3%没有),无复发无病存活率没有显著差异.
结论:
- 乳房切除似乎是一种安全和可行的初始手术治疗单边低风险乳头甲状腺癌 (PTC) 与相反的低至中等可疑结节.
- 在这种情况下,逆侧结节表现出一般稳定或回归的行为,发展为PTC的风险很低.
- 腰椎切除术提供了有利的长期结果,支持其作为适当的手术管理策略的考虑.
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