拒绝输血的胃肠道出血患者的管理和临床结果
Jessica O Asiedu1, Ananda J Thomas1, Nicolas C Cruz1
1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, United States of America.
PloS one
|August 25, 2023
概括
无血医学技术有效地管理拒绝输血的患者的胃肠道出血. 侵袭性贫血治疗甚至稳定了临界低的血红蛋白水平,改善了患者的治疗结果.
科学领域:
- 医学科学 医学科学 医学科学
- 血液学 血液学 血液学
- 胃肠病学 胃肠病学
背景情况:
- 全国血液短缺需要无血药的倡议.
- 越来越多的患者拒绝输血,需要采用替代的治疗策略.
- 胃肠道出血对于输血依赖的护理具有独特的挑战.
研究的目的:
- 描述了拒绝全基血输血的胃肠道出血患者的治疗方法.
- 在这个患者群体中评估无血医学技术的有效性.
- 为未来的治疗策略提供信息,并减少输血相关的风险和成本.
主要方法:
- 对30例住院患者的胃肠道出血病例 (2016-2022) 的回顾性图表审查.
- 对患者血液管理方法,临床特征和结果的分析.
- 报告血红蛋白度和治疗反应.
主要成果:
- 静脉注射铁 (83.3%) 和红素 (60.0%) 是常见的治疗方法.
- 内镜 (76.7%) 经常进行;手术较少 (13.3%).
- 血红蛋白中位数为5.6g/dL,治疗后增加到7.3g/dL;大多数Hb<5g/dL的患者存活下来.
结论:
- 胃肠道出血患者可以使用无血医学技术成功治疗.
- 侵略性贫血治疗稳定了低血红蛋白患者,使得内镜或手术等手术成为可能.
- 无血医学策略可以提高所有患者的临床护理,而不仅仅是那些拒绝输血的人.
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