菌类病原体和COVID-19的疾病
Ashutosh Singh1, Amtoj Kaur2, Anuradha Chowdhary1
1Medical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India; National Reference Laboratory for Antimicrobial Resistance in Fungal Pathogens, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Current opinion in microbiology
|August 25, 2023
概括
随着COVID-19大流行,二次真菌感染的数量增加,如阿斯伯吉洛症和甘地菌症,死亡率增加. 诊断和治疗的挑战加剧了这些侵袭性真菌感染在重症患者的结果.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 菌类学 菌类学是指菌类学.
背景情况:
- COVID-19 流行病与严重病例中二次真菌感染的显著增加有关.
- 免疫抑制,免疫调节疗法和侵入性手术等因素有助于COVID-19患者的敏感性增加.
- 这些真菌感染加剧了患者的结果,导致长时间住院和增加死亡率.
研究的目的:
- 审查COVID-19患者中二次真菌感染的流行病学和临床影响.
- 要突出常见的真菌病原体及其在这个患者群体中的全球分布.
- 讨论诊断和治疗这些感染的挑战.
主要方法:
- 对报告COVID-19患者真菌感染的研究的文献综述.
- 报告的真菌物种,流行率和地理分布的分析.
- 检查诊断障碍和治疗限制.
主要成果:
- 阿斯伯吉洛症,侵袭性角膜病症和粘菌菌是最常见的真菌感染.
- 在全球范围内,疹病和阿斯伯吉洛斯病病例的增加,而粘菌菌病的爆发主要发生在印度.
- 这些感染显著影响患者的发病率和死亡率.
结论:
- 二次性真菌感染对COVID-19患者,特别是重症监护室患者构成重大威胁.
- 诊断困难和有限的治疗选择导致管理不善和较高的死亡率.
- 需要进一步的研究和改进的临床策略来解决这一日益严重的公共卫生问题.
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