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Updated: Jul 18, 2025

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish
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doxorubicin 诱导的心血管毒性:功能和分子标记物的纵向评估

Matthias Bosman1, Dustin Krüger1, Charles Van Assche2

  • 1Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, Antwerp B-2610, Belgium.

Cardiovascular research
|August 25, 2023
PubMed
概括

在心脏功能降低之前,多克索鲁比 (DOX) 会导致动脉硬和内皮功能障碍. 新的生物标志物 - - 血栓松丁-1 (THBS1) 和α-1-抗基莫素 (SERPINA3) - - 对检测DOX诱导的心血管毒性显示出希望.

关键词:
动脉的硬性 动脉的硬性心脏有毒性 - 心脏有毒性德克索鲁比辛是一种多克索鲁比辛.内皮质功能障碍 内皮质功能障碍

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