给编辑的信: 在尿液药物测试中的欺骗观察
Agnes Cua1, Kevin Krock1, Richard Thomas1
1Precision Diagnostics LLC San Diego CA, USA.
Annals of clinical and laboratory science
|August 25, 2023
概括
代谢物/原始药物比率可以检测尿液药物测试中的欺骗. 在研究的药物中,布普伦诺芬最常涉及这种欺骗类型.
科学领域:
- 法医毒理学 法医毒理学
- 分析化学 分析化学
背景情况:
- 尿液药物检测对于监测患者遵守处方药物的关键.
- 患者可能会试图通过提交原始药物而没有摄入这些药物来欺骗药物测试.
研究的目的:
- 确定用于检测尿液药物测试欺骗的方法.
- 评估代谢物/原始药物比率在发现欺诈样本方面的有用性.
主要方法:
- 对五种常见药物的分析:氧化,化,布普伦诺芬,甲和芬太尼.
- 计算每个样本的代谢物/原始药物比率.
- 比例的比较,以识别潜在的欺骗.
主要成果:
- 代谢物/原始药物比率有效地识别出欺骗尿液药物测试的企图.
- 在测试物质中,布普伦诺啡因被观察到是与这种欺骗性做法相关的最常见药物.
结论:
- 代谢物/原始药物比率是尿液药物检测中欺骗的可靠指标.
- 这种方法有助于确保药物测试结果的完整性,特别是在布诺芬.
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