夜间动荡:从睡眠状态解离到与睡眠有关的解离状态
R Lopez1, J-A Micoulaud-Franchi2, L Peter-Derex3
1National Reference Centre for Orphan Diseases, Narcolepsy-Rare hypersomnias, Sleep Unit, Department of Neurology, CHU de Montpellier, University of Montpellier, Montpellier, France; Institute for Neurosciences of Montpellier (INM), University of Montpellier, Inserm, Montpellier, France.
Revue neurologique
|August 25, 2023
概括
区分非快速眼动 (NREM) 睡眠障碍和与睡眠相关的分离性障碍 (SRDD) 之间的区别对于有效治疗至关重要. 这两种情况都涉及睡眠-清醒分离,但在呈现,发生和潜在的创伤联系方面有所不同.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 夜间动包括多种不同的行为,需要准确的病因识别治疗.
- 区分非快速眼动 (NREM) 睡眠障碍与精神性非睡眠障碍的表现,例如与睡眠相关的分离性障碍 (SRDD),具有临床挑战,特别是在年轻人群中.
研究的目的:
- 审查当前的临床,神经生理学和流行病学数据关于NREM睡眠障碍症和SRDD.
- 探索这些夜间表现的潜在病理生理学假设.
主要方法:
- 文献综述综合临床观察.
- 神经生理学发现分析.
- 流行病学数据的检查.
主要成果:
- NREM 睡眠障碍 (睡眠行走,睡眠恐惧,混性唤醒) 通常发生在睡眠开始后,涉及简短,拙的行为,并显示成人患病率下降.
- NREM 类睡眠症患者表现出分离的大脑活动:激活了运动/边缘区域,并保持了前侧-双侧睡眠.
- SRDD涉及长期的,戏剧性的,经常具有侵略性的情节,经常与心理创伤有关,并且发生在接近清醒时.
结论:
- NREM 类睡眠障碍症和SRDD可能代表与睡眠有关的分离状态的形式.
- 这两种情况都可能受到睡眠开始或唤醒期间的睡眠-清醒状态解离的影响.
- 进一步研究SRDD病理生理学是有必要的,考虑到其与创伤和独特的临床特征的关联.
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