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Updated: Jun 21, 2026

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Nrf2可以缓解太空飞行引起的免疫抑制和小鼠的血栓性微血管病变

Ritsuko Shimizu1,2,3, Ikuo Hirano4, Atsushi Hasegawa5

  • 1Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. rshimizu@med.tohoku.ac.jp.

Communications biology
|August 25, 2023
PubMed
概括

缺乏Nrf2基因的小鼠在太空飞行期间经历了更严重的免疫抑制和炎症. 这凸显了Nrf2在减轻太空飞行引起的健康风险方面的关键作用.

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...