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Updated: Jul 18, 2025

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
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不活跃的X染色体随着年龄的增长积累了广泛的表观遗传变异性

Yunfeng Liu1, Lucy Sinke1, Thomas H Jonkman1

  • 1Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Postzone S-5-P, 2333 ZC, Leiden, The Netherlands.

Clinical epigenetics
|August 25, 2023
PubMed
概括

女性的表观遗传变化表明,随着年龄的增长,DNA甲基化变异性在不活跃的X染色体上增加,这表明X染色体不活化中断和衰老之间存在联系.

关键词:
衰老的衰老 衰老的衰老通过DNA甲基化.基因表达 基因表达 基因表达差异差异是指差异的差异.女人 女人 女人 女人 女人一个X染色体是X染色体.

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