手握运动不会改变CO2介导的大脑血管流介导的扩张
Shotaro Saito1, Hironori Watanabe1, Erika Iwamoto2
1Department of Biomedical Engineering, Toyo University, Kawagoe, Japan.
Experimental physiology
|August 26, 2023
概括
急性握手运动暂时改善了认知功能,但没有增强大脑内皮功能. 这表明,改善血流调节并不是掌握炼对认知益处的主要机制.
科学领域:
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
- 心血管研究研究心血管研究
背景情况:
- 众所周知,手握运动 (HG) 可以改善认知功能,并被认为有助于保持大脑健康.
- HG对大脑血流调节,特别是内皮功能的确切影响仍然不完全理解.
- 大脑内皮功能对于调节大脑血液流动至关重要.
研究的目的:
- 研究间隔握手运动对健康年轻人脑内皮功能的急性影响.
- 为了确定大脑内皮功能变化是否调解了手握运动后观察到的认知改善.
主要方法:
- 参与者在25%的最大自愿收缩时进行了4次2分钟间隔握手练习,并进行了3分钟的恢复期.
- 在运动前后使用Go/No-Go任务 (测量反应时间和准确性) 评估认知表现.
- 大脑内皮功能通过测量内动脉 (ICA) 脑血管流介导扩张 (cFMD) 来评估.
- 使用双重多普勒超声波计算内动脉剪切率 (SR).
主要成果:
- 认知表现,特别是反应时间,在运动后5分钟显著改善 (P=0.008).
- 然而,运动期间的内动脉剪切率和运动后的脑血管流介导扩张保持不变 (分别P=0.313和P=0.440).
结论:
- 在健康的年轻人中,急性间隔握手运动似乎没有增强大脑内皮功能.
- 在握手运动后观察到的短期认知改善可能不会通过大脑内皮功能增强来调解.
- 急性握手运动的强度或持续时间可能不足以刺激脑血管剪切率和内皮反应的显著变化.
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