影响物质使用障碍治疗短期成功的变量中的性别差异
Kishan Desai1, Vivian Hagerty1, Varun Hariharan1
1Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
Journal of addictive diseases
|August 26, 2023
概括
较长的治疗停留时间与物质使用障碍 (SUD) 的治疗失败相关. 识别患者的特征可以个性化SUD治疗并改善结果.
科学领域:
- 成 药物 药物 药物 药物
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 耻辱和后续挑战限制了物质使用障碍 (SUD) 结果数据.
- 现实世界的数据对于理解SUD中治疗完成至关重要.
- 急性治疗完成率对于患者的康复和公共健康至关重要.
研究的目的:
- 为了确定与急性治疗完成相关的患者特征在物质使用障碍 (SUD) 中.
- 探索性别之间的治疗成功和失败预测因素的差异.
- 根据个体患者的个人资料,为SUD提供个性化的治疗策略.
主要方法:
- 从单个SUD治疗设施中从1039名患者收集前性数据.
- 在治疗时对43个不同的患者特征进行多变量分析.
- 将成功定义为计划放弃,而失败定义为复发或违背医疗建议离开.
主要成果:
- 较长的停留时间与总队列和两性治疗失败有关 (p ≤0.01).
- 女性特有的成功预测因素包括以目标为导向的思维 (p ≤0.05).
- 女性特有的失败预测因素包括冒险 (p < 0.05),详细的自杀计划 (p ≤ 0.001) 和狭的思维 (p ≤ 0.01).
- 失败的男性特异性预测因素包括先前的DUI逮捕 (p ≤0.05) 和恐惧症,偏执或妄想的存在 (p ≤0.05).
结论:
- 患者的特征显著影响物质使用障碍 (SUD) 的急性治疗结果.
- 根据性别和个体特征进行分层SUD治疗对于提高成功率至关重要.
- 以已识别的风险因素为指导的个性化治疗方法可以促进患者从SUD中恢复.
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