COVID-19 和神经系统表现
Kathleen Forero1, Raghad Buqaileh1, Clare Sunderman1
1Department of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USA.
Brain sciences
|August 26, 2023
概括
本综述涵盖了2019年冠状病毒病 (COVID-19) 症状,重点关注神经效应. 它探讨了SARS-CoV-2如何通过ACE2受体感染人体,影响多个器官.
科学领域:
- 病毒学 病毒学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 通过空气传播引起全球大流行.
- 该病毒与血管酶转化酶2 (ACE2) 受体结合,这些受体存在于肺,心脏,胃肠道和大脑等器官中.
研究的目的:
- 审查有关COVID-19症状的当前知识.
- 要突出与COVID-19相关的神经症状.
- 讨论人体中SARS-CoV-2感染的潜在机制.
主要方法:
- 关于SARS-CoV-2现有研究的文献综述.
- 对报告的COVID-19症状进行分析,重点关注神经表现.
- 检查ACE2受体在病毒病原发生中的作用.
主要成果:
- COVID-19呈现出一系列症状,包括显著的神经效应.
- ACE2受体对于SARS-CoV-2进入各种细胞类型至关重要.
- 病毒可以影响呼吸道以外的多个器官系统.
结论:
- 了解COVID-19的各种症状,特别是神经症状,对于患者管理至关重要.
- SARS-CoV-2和ACE2受体之间的相互作用为病毒的广泛影响提供了洞察力.
- 需要进一步的研究,以充分阐明SARS-CoV-2感染的机制及其长期后果.
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