对Cryptosporidium spp. 的侧流试验的临床性能 诊断 诊断 诊断 诊断 诊断
Miriam Campos-Ruiz1,2, Clara Flamarich3, Anabel Fernández-Navarro1,2
1Microbiology Department, Clinical Laboratory North Metropolitan Area, Germans Trias i Pujol University Hospital, 08916 Badalona, Spain.
Biomedicines
|August 26, 2023
概括
寄生虫Cryptosporidium在人类中引起胃肠炎. 这项研究发现,巴塞罗那的患病率为2%,夏季末和秋季达到顶峰,这凸显了常规检测的必要性.
科学领域:
- 医学寄生虫学 医学寄生虫学
- 传染病 流行病学 流行病学
- 公共卫生 微生物学
背景情况:
- 克里普托斯波里迪亚物种是人类胃肠炎的原生虫寄生虫.
- 西班牙报告说,2018年有1511例确诊病例的增长趋势.
- 准确诊断密码菌病对于预防疾病传播至关重要,但在常规的寄生虫学研究中经常被忽视.
研究的目的:
- 在对Cryptosporidium spp.进行测试的患者中调查密码杆菌的循环和流行病学. 在巴塞罗那北部大都会地区,马雷斯梅和西部谷区.
- 评估研究群体中密码菌病的流行情况并确定密码菌病的关键流行病学特征.
主要方法:
- 用于便样本分析,采用了两步诊断算法.
- 在Cryptosporidium/Giardia spp.的研究中. 免疫染色学测试用于初始查.
- 通过显微镜检查和光染色确认了阳性样本.
主要成果:
- 大约2%的研究患者的测试结果为Cryptosporidium spp.阳性.
- 在夏末和秋初观察到一个明显的季节性发病率峰值.
- 确诊病例中体重减轻是主要症状,这些人平均年龄 (19岁) 比未确诊患者年轻.
结论:
- 克里普托斯波里迪亚 spp. 在被研究的欧洲地区积极流通.
- 这些发现强调了在诊断策略中考虑密码菌病的流行程度的重要性.
- 建议积极监测和例行测试,以有效控制密码菌病.
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