Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cause and Effect01:53

Cause and Effect

10.9K
While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
10.9K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

196
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
196
Understanding Sleep01:11

Understanding Sleep

408
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
408
Biological Influences on Intelligence01:30

Biological Influences on Intelligence

144
Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
144
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

171
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
171
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Cerebral Glucose Hypometabolism in Alzheimer's Disease: A Meta-Analysis and Transcriptomic-Neuroimaging Study.

Current Alzheimer research·2026
Same author

Functional Brain Network Predictors of Abstinence Treatment Outcomes in Methamphetamine Use Disorder.

CNS neuroscience & therapeutics·2026
Same author

Longitudinal Multiparametric Quantitative MRI Evaluation of Graft Maturity Following Anterior Cruciate Ligament Reconstruction: A One-Year Prospective Observational Study.

Diagnostics (Basel, Switzerland)·2026
Same author

Accelerated brain aging in methamphetamine use disorder revealed by functional connectivity.

National science review·2026
Same author

Gut-Brain Connection: Deciphering Causal Pathways Between Gut Microbiota and Neuroimaging Profiles Through Mendelian Randomization.

Food science & nutrition·2026
Same author

Crosstalk of peripheral cytokine-white matter alteration-insomnia during methadone maintenance treatment.

Psychological medicine·2026

相关实验视频

Updated: Jul 18, 2025

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

7.9K

睡眠特征因果关系影响大脑皮层结构:孟德尔的随机化研究

Yanjing Chen1, Shiyi Lyu1, Wang Xiao2

  • 1Department of Radiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Biomedicines
|August 26, 2023
PubMed
概括

短暂的睡眠与大脑结构的变化有关,可能增加神经精神疾病的风险. 需要进一步的研究来证实睡眠特征和皮质改变之间的这些关联.

关键词:
大脑皮质结构 大脑皮质结构大脑皮层表面积 (SA)皮层厚度 (TH) 皮层厚度 (TH)门德尔的随机化是门德尔的随机化睡眠 睡眠 睡眠 睡眠 睡眠

更多相关视频

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
03:46

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Published on: October 11, 2018

10.1K

相关实验视频

Last Updated: Jul 18, 2025

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

7.9K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
03:46

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Published on: October 11, 2018

10.1K

科学领域:

  • 神经成像是一种神经成像.
  • 睡眠科学 睡眠科学
  • 遗传学 是一个遗传学.

背景情况:

  • 睡眠不足会影响大脑皮层结构.
  • 底层机制需要进一步研究.

研究的目的:

  • 探索睡眠特征和皮质结构之间的因果关系.
  • 研究早晨,睡眠时间和失眠与大脑解剖学的关联.

主要方法:

  • 使用磁共振成像 (MRI).
  • 使用孟德尔随机化 (MR) 评估因果关系.
  • 评估了五种睡眠特征:清晨,容易醒来,失眠,长时间睡眠和短时间睡眠.

主要成果:

  • 晨与皮表面积 (SA) 的增加有关.
  • 短暂的睡眠与横向尾SA增加以及降低对中心和对海马皮层皮层厚度 (TH) 相关.
  • 没有观察到类,但Bonferroni纠正值未达到因果关系.

结论:

  • 研究结果表明,副中心和副海马缩以及中皮层增加与神经精神疾病之间存在潜在的联系.
  • 突出了皮层结构和五种睡眠特征之间的关联.
  • 需要进一步的研究来验证这些发现.