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Updated: Jul 18, 2025

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在Cyp19-Cre ROSAmT/mG转基因小鼠的胎盘中可变的Cre重组效率

Prashanth Anamthathmakula1,2, Philemon D Shallie1,2, Neha Nayak1

  • 1Department of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.

Cells
|August 26, 2023
PubMed
概括

芳香酶-克里 (Cyp19-Cre) 鼠标模型显示出由于马赛克主义和原产地父效应而导致不一致的胎盘特异性基因失活. 研究人员发现了可变的重组活性,影响了使用这种模型进行胎盘基因研究的研究.

关键词:
创建激活中的激活.这就是Cyp19-Cre.胎盘 胎盘 胎盘 胎盘

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
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