将瘤基础数据集映射到共同数据模型的标准化词汇:可行性研究
Jasmin Carus1,2,3, Leona Trübe1, Philip Szczepanski2
1Institute for Applied Medical Informatics, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Cancers
|August 26, 2023
概括
将德国瘤基础数据集 (oBDS) 映射到OMOP共同数据模型 (CDM) 中,提高了癌症数据的互操作性. 这促进了国家研究网络和联合分析,以改善癌症洞察力.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 数据标准化数据标准化
背景情况:
- 德国医疗保健部门要求向注册局报告癌症患者的数据.
- 瘤基础数据集 (oBDS) 是国家标准,但软件变异导致数据异质.
- 这种异质性阻碍了研究网络和集体癌症数据分析.
研究的目的:
- 评估所有oBDS特征的可转移性到观察医学结果伙伴关系 (OMOP) 共同数据模型 (CDM) 的词汇.
- 评估德国癌症数据标准化研究的可行性.
主要方法:
- 将 17,844 个 oBDS 表达式映射到 OMOP CDM 标准化概念 (自动和手动).
- 从汉堡癌症登记处转换到OMOP CDM术语中的真实患者数据.
- 开发了用于瘤学数据的数据转换管道.
主要成果:
- 成功地将OBDS表达式映射到OMOP CDM标准化词汇库中.
- 从汉堡癌症登记处转换了1,773,373个与癌症相关的数据元素到OMOP CDM.
- 证明了大规模瘤数据标准化的可行性.
结论:
- 将oBDS映射到OMOP CDM促进了德国瘤数据的语义互操作性.
- 允许参与国际研究网络,如观察健康数据科学和信息学 (OHDSI).
- 促进跨越国家边界的癌症数据的联合分析.
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