人类乳头瘤病毒相关的口腔癌:全球流行病学和公共政策影响
Sifon Ndon1, Amritpal Singh2, Patrick K Ha1
1Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA 94115, USA.
全球趋势显示,与人类乳头瘤病毒 (HPV) 相关的口腔癌在北美,欧洲和大洋洲的最高. 性别中立的HPV疫苗接种政策并不普遍,特别是在低收入国家.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 人类乳头瘤病毒 (HPV) 相关的头癌 (HNC),特别是口腔状细胞癌 (OPSCC) 的全球趋势正在演变.
- 与HPV相关的OPSCC发病率存在区域差异,影响分期和治疗.
- 预防HPV疫苗接种是预防的关键,但政策有所不同,特别是在性别中立和低收入和中等收入国家.
研究的目的:
- 在全球范围内审查与HPV相关的OPSCC发病率的区域变化.
- 检查全球性别中立的HPV疫苗接种政策的现状.
- 确定了解与HPV相关的OPSCC趋势和疫苗接种范围的研究缺口.
主要方法:
- 对HPV相关OPSCC的流行病学研究的文献综述.
- 分析全球HPV疫苗接种政策,包括性别中立的覆盖范围.
- 根据地区编制有关发病率和接种疫苗的数据.
主要成果:
- 在北美,欧洲和大洋洲观察到与HPV相关的OPSCC的最高发病率.
- 截至2022年,63%的世卫组织成员国拥有国家HPV疫苗接种计划.
- 只有34%的这些成员国提供了性别中立的HPV疫苗接种.
结论:
- 在与HPV相关的OPSCC发病率方面存在显著的区域差异.
- 全球需要更广泛地实施性别中立的HPV疫苗接种政策.
- 进一步的研究对于了解风险因素和HPV相关OPSCC的发展趋势至关重要.
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