OSCC的转移基于口腔状体的Ruber Planus
Katharina Theresa Obermeier1, Sabina Noreen Wuersching2, Paris Liokatis1
1Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, Ludwig Maximilian University Munich, 80337 Munich, Germany.
Cancers
|August 26, 2023
概括
口腔状皮平原 (OLP) 可以转化为口腔状细胞癌 (OSCC),转移风险较低,但二次瘤的风险更高. 对这些患者来说,仔细的随访至关重要.
科学领域:
- 口腔医学是指口腔医学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 口腔状菌平原 (OLP) 是一种慢性炎症性口腔粘膜疾病.
- 恶性转变为口腔状细胞癌 (OSCC) 发生在1-2%的OLP病例中.
- 由于瘤特征,与OLP相关的OSCC的治疗仍在争论中.
研究的目的:
- 为了比较具有OSCC的OLP患者的转移发育和存活率与没有OLP的OSCC患者.
- 分析在OLP的背景下出现的OSCC的特征.
主要方法:
- 对103名为OLP治疗的患者的回顾性概述.
- 与OLP相关的OSCC和非OLPOSCC群体之间的转移率和存活率的比较.
主要成果:
- 在OLP患者中,OSCC显示淋巴结扩散的风险显著降低 (p=0.013).
- 没有OLP的OSCC患者的淋巴结扩散风险增加了4.76倍.
- 在患有与OLP相关的OSCC的患者中,第二次超慢性瘤的发生频率更高.
结论:
- 基于OLP的OSCC在女性中更常见,高度差异化,转移风险较低,但第二种瘤的风险更高.
- 对于与OLP相关的OSCC,需要特别注意和谨慎的辅助治疗计划.
- 由于复发或新的原发性瘤的风险,密切的临床随访至关重要.
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