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子与地板养殖系统对子生长表现和免疫状况的影响和机制

Bincheng Tang¹, Shenqiang Hu¹, Xin Zhang¹

¹Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.

Animals : an open access journal from MDPI

|August 26, 2023

概括

地板养系统 (FRS) 增强的生长,而养系统 (CRS) 提高免疫功能,由更高的免疫球蛋白G (IgG) 和介质蛋白-6 (IL-6) 水平证明. 通过氨酸代谢,CRS可以提高免疫力.

科学领域:

动物科学动物科学
免疫学免疫学免疫学
基因组学就是基因组学.

背景情况:

地板养系统 (FRS) 和养系统 (CRS) 是主要的生产方法.
FRS和CRS对的生长,健康和潜在的分子机制的比较影响需要进一步阐明.

研究的目的:

为了比较FRS和CRS下的的生长性能和免疫状态.
为了研究在FRS下养的子中脏组织的全基因组转录基因组概况,与270天的CRS相比.

主要方法:

身体体重,体型和器官指数的表型分析 (脏,Fabricius的囊).
对免疫球蛋白G (IgG) 和介质蛋白-6 (IL-6) 水平的血清分析.
使用RNA测序对脏组织进行全基因组的转录分析,随后进行差异基因表达分析和蛋白质-蛋白质相互作用网络分析.

主要成果:

在FRS下,与CRS相比,的体重和体型显著增加 (p < 0.05).
在CRS的中,的脏重量和器官指数显著增加,Fabricius的囊保留,血清IgG和IL-6水平升高 (p <0.05).
转录组分析显示,脏中251个差异表达基因 (DEGs),富含免疫反应,炎症反应和氨酸代谢途径. 确定了包括VEGFA,FGF2和CD36在内的关键候选基因.

结论:

地板养殖系统 (FRS) 促进的优越生长性能.
养系统 (CRS) 增强的免疫功能,由血清IL-6和IgG的增加表明,并可能通过氨酸代谢途径进行介导.
该研究提供了关于FRS和CRS对体生理和免疫力的差异影响的宝贵见解,有助于优化养策略.

关键词:

四川白是什么意思四川白是什么意思增长表现成绩增长的表现.免疫状态免疫状态养殖系统的养殖系统.转录基因分析

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Imprinting

Imprinting

Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.