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COVID-19和男性不孕症:抗氧化剂有没有作用?

Thomas Kalfas¹, Aris Kaltsas², Evangelos N Symeonidis³

¹Independent Researcher, 43100 Karditsa, Greece.

Antioxidants (Basel, Switzerland)

|August 26, 2023

概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 通过影响丸功能和引起氧化应激会影响男性生育能力. 在COVID-19后改善精子质量的抗氧化剂有效性仍未得到证实.

科学领域:

生殖医学生殖医学
传染性疾病传染性疾病
氧化压力研究研究氧化压力研究

背景情况:

冠状病毒疾病19 (COVID-19),由SARS-CoV-2引起,对男性生殖健康构成风险.
男性的生殖系统,特别是丸,容易受到病毒损伤和相关的氧化应激.
了解COVID-19对男性生育能力的影响对于公共卫生和生殖医学至关重要.

研究的目的:

评估SARS-CoV-2感染对男性丸功能的影响.
调查氧化应激在COVID-19相关男性不孕症中的作用.
检查抗氧化剂在减轻丸损伤方面的潜在益处.

主要方法:

使用PubMed.com进行了全面的文献综述.
对丸外分和内分泌功能变化的研究分析.
检查氧化应激和COVID-19引起的生育缺陷之间的相互作用.

主要成果:

COVID-19影响精液质量和荷尔蒙平衡,有一些持续变化.
已故患者的丸病理显示出精子生成缺陷,血管变化和炎症.
升高的氧化应激和精子DNA碎片化表明氧化还原失衡是关键机制.

结论:

COVID-19可以通过包括氧化应激在内的各种机制对男性生育能力产生负面影响.
虽然COVID-19疫苗似乎对男性生育能力安全,但感染后抗氧化剂的有效性尚未被证明.
需要进一步的研究,并建议对在COVID-19后寻求生育能力改善的男性进行仔细评估.

关键词:

在 COVID-19 疫情中,这就是SARS-CoV-2病毒.抗氧化剂抗氧化剂是一种抗氧化剂.男人不孕不育的原因氧化应激是一种氧化应激.有活性氧物种的反应性氧物种.

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