使用世卫组织访问,观察和储备分类对抗生素处方模式的评估在刚果民主共和国金沙萨
Jocelyn Mankulu Kakumba1, Jérémie Mbinze Kindenge1, Paulin Mutwale Kapepula2
1Laboratory of Drug Analysis, Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa XI 212, Democratic Republic of Congo.
Antibiotics (Basel, Switzerland)
|August 26, 2023
概括
这项研究揭示了刚果民主共和国的抗生素分配不足,使用的高比例是观察和不推的抗生素. 在对抗抗微生物药物耐药性方面,对卫生工作者对世卫组织的AWaRe分类进行培训至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 世界卫生组织 (WHO) 开发了AWaRe工具,通过将抗生素分为四组:获取,观察,储备和不推,以促进合理的抗菌药物使用.
- 根据刚果民主共和国AWaRe分类的抗生素分发模式的数据有限.
- 这项研究旨在分析与世卫组织AWaRe分类相关的抗生素分发模式,以支持国家抗菌素耐药性计划.
研究的目的:
- 在刚果民主共和国金沙萨的Tshangu区的卫生专业人员中调查抗生素分发模式.
- 根据世卫组织的AWaRe类别 (获取,观察,储备,不推) 将分发的抗生素分类.
- 提供可以加强国家抗微生物耐药性战略的数据.
主要方法:
- 一项调查于2022年7月至12月在金沙萨的Tshangu地区进行.
- 从随机选择的药店收集数据,包括对药品销售商的采访和从客户处方的收集.
- 处方抗生素使用WHO AWaRe分类进行分类,并根据每处方的抗生素数量进行分析.
主要成果:
- 在400份收集的处方中,有301份 (75.25%) 含有抗生素.
- 总共有463种抗生素被处方:169种 (36.5%) 来自访问组,200种 (43.2%) 来自观察组和94种 (20.3%) 来自不推组.
- 第三代头素 (34.33%) 和青素 (17.17%) 是最常见的抗生素类别,Ceftriaxone是最常见的单独抗生素 (21.38%).
结论:
- 该研究强调了抗生素分发的令人担忧的趋势,显著使用观察和不推的抗生素.
- 严格执行打击抗微生物药物耐药性的国家计划至关重要.
- 为改善抗生素管理,对卫生保健工作人员正确应用世卫组织AWaRe分类的培训至关重要.
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