实验室监测,质量管理及其在解决非洲抗菌素耐药性的作用:叙述性审查
Khalid Musa1,2, Ijeoma Okoliegbe1, Tassabeeh Abdalaziz1,2
1Department of Medical Microbiology and Virology, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK.
Antibiotics (Basel, Switzerland)
|August 26, 2023
概括
抗菌素耐药性 (AMR) 是一个关键的全球卫生问题,特别是在非洲,由高传染病率和软弱的监管系统驱动. 加强监测和实验室能力对于应对这种日益增长的威胁至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 全球卫生安全 全球卫生安全
背景情况:
- 抗菌素耐药性 (AMR) 对全球公共卫生,经济和社会构成重大威胁.
- 非洲国家感染性疾病的高流行率有助于广泛使用抗生素和AMR的出现.
- 不充分的药物监管,不良的处方实践和有限的公共卫生举措加剧了非洲的AMR挑战.
研究的目的:
- 突出非洲抗菌素耐药性 (AMR) 的多方面的挑战.
- 为了强调在非洲实验室实施有效的抗菌素耐药性监测和质量保证计划的困难.
- 确定导致非洲抗菌药物耐药性增加和扩散的关键因素.
主要方法:
- 对非洲抗菌药物耐药性的现有文献和监测数据的审查.
- 分析导致AMR的因素,包括公共卫生基础设施和监管框架.
- 检查对抗敏药性监测实验室能力和质量保证的挑战.
主要成果:
- 非洲实验室在建立强有力的AMR监测质量保证计划时面临重大障碍.
- 缺乏实验室能力,数据管理不足和合作不佳,阻碍了有效监测AMR.
- 现有的倡议,如世卫组织的GLASS和非洲疾病预防控制中心的AMRSNET,旨在加强AMR监测.
结论:
- 解决非洲的抗菌药物耐药性需要采用多学科的方法,并对实验室基础设施和监测系统进行大量投资.
- 加强监管监督和公共卫生干预措施对于制抗菌素耐药性传播至关重要.
- 加强国际和区域合作对于有效的全球抗菌耐药性制战略至关重要.
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