光疗外体膜氧化器的设计优化,用于治疗一氧化碳中毒
Edidiong Etim1, Anastasia Goulopoulos1, Anna Fischbach2
1Department of Biomedical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Bioengineering (Basel, Switzerland)
|August 26, 2023
概括
这项研究引入了一种新型的照片ECMO设备,该设备使用可见光加速从血红蛋白中去除一氧化碳 (CO). 优化的设计减少了血液停滞,可能减少CO中毒的治疗时间.
科学领域:
- 生物医学工程 生物医学工程
- 支持心肺血管的支持.
- 摄影化学的使用.
背景情况:
- 一氧化碳 (CO) 中毒是一个重大的公共卫生问题.
- 目前用于CO中毒的治疗方法可能耗时.
- 血红蛋白 (Hb) CO 分离是加速去除的目标.
研究的目的:
- 设计和计算建模一个光外体膜氧化 (Photo-ECMO) 装置.
- 用可见光来提高从血液中去除CO的速度.
- 优化设备几何形状,以实现高效的血液流动和光线透.
主要方法:
- 使用了计算流体动力学 (CFD) 模拟.
- 纳维埃-斯托克斯和对流-扩散方程模拟了血流和热负荷.
- 为了分析流动力学,在设备几何上应用了不同半径的片.
- 计算了颗粒的停留时间,以评估血液暴露的持续时间.
主要成果:
- filet半径的增加减少了血流停滞.
- 设备内的最大温度升高保持在4°C以下.
- 确定了一种优化的设备,其片半径为5厘米,原始体积为208厘米.
结论:
- 优化的照片ECMO设备显示了在患者中更快地去除CO的潜力.
- 设计尽量减少血液成分的热应力.
- 这项技术可以显著改善CO中毒和气体交换抑制的结果.
相关概念视频
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
688
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
688
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
263
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
263
Oxygen Delivering System I: Nasal Cannula and Face Mask
384
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
384
Administering Oxygen by Mask
440
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
440
Assessment of Diffusion and Perfusion
1.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.0K
Special considerations while measuring oxygen saturation
612
Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
612


