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前列腺体积对前列腺成像和报告数据系统 (PI-RADS) 在现实世界的环境中的影响

Yannic Volz¹, Maria Apfelbeck¹, Nikolaos Pyrgidis¹

¹Department of Urology, LMU Klinikum, Ludwig-Maximilians University, Marchioninistr. 15, 81377 Munich, Germany.

Diagnostics (Basel, Switzerland)

|August 26, 2023

概括

大的前列腺体积显著降低了多参数MRI (mpMRI) 导向活检中的癌症检测率,特别是在PI-RADS 4和5病变中. 当前列腺体积超过特定值时,临床意义上的前列腺癌检测不太可靠.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
放射学放射学是一门学科.
在瘤学瘤学.

背景情况:

多参数磁共振成像 (mpMRI) 对于诊断前列腺癌至关重要.
前列腺体积可以影响mpMRI上临床显著前列腺癌 (csPCa) 的检测率.
需要进一步澄清PI-RADS得分,前列腺体积和csPCa检测之间的关系.

研究的目的:

在现实环境中评估前列腺体积,PI-RADS得分和csPCa检测率之间的关联.
定义特定的前列腺体积切断值,显著损害mpMRI向活检的有效性.

主要方法:

对1039名连续接受mpMRI导向前列腺活检的患者进行了回顾性分析.
包括1151个PI-RADS目标,由各种放射学办公室进行评估.
ROC分析以确定PI-RADS 3,4和5病变的前列腺体积切线值.

主要成果:

对于PI-RADS 4病变,前列腺体积>61.5厘米显著降低了csPCa检测 (或0.24).
对于PI-RADS 5病变,前列腺体积大于51.5厘米显著降低了csPCa检测 (或0.39).
对于PI-RADS 3病变,前列腺体积对csPCa检测没有显著的影响.

结论:

扩大前列腺体积是mpMRI向前列腺活检的日常实践中的一个显著限制.
这项研究提供了第一个精确的前列腺体积值,影响PI-RADS在现实环境中的有效性.
在前列腺体积超过定义值的患者中,mpMRI向活检结果需要仔细解释.

关键词:

这就是为什么MRI是MRI.皮拉德斯 (PI-RADS) 是一个活组织活检诊断的准确性诊断的准确性前列腺癌是前列腺癌.前列腺的体积,前列腺的体积.

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