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功能性MRI侧向化[M1]dlPFC和对跨磁刺激 (TMS) 向向的影响

Jean Rama Surya¹, Barshen Habelhah¹, Jonathan Haroon¹

¹Neurological Associates-The Interventional Group, 2811 Wilshire Blvd #790, Santa Monica, CA 90403, USA.

Diagnostics (Basel, Switzerland)

|August 26, 2023

概括

这项研究探索了一项脑扫描任务,以绘制背侧前额皮层 (dlPFC) 半球主导的地图. 研究结果表明,这种方法可以优化TMS等干预措施的脑刺激目标.

科学领域:

神经科学是一个神经科学.
认知神经科学认知神经科学
脑部成像脑部成像

背景情况:

脊侧侧前额皮质 (dlPFC) 的功能横向化对于神经外科手术和跨磁刺激 (TMS) 的有效性至关重要.
精确的dlPFC定位可以最大限度地降低干预风险,并提高治疗的有效性.

研究的目的:

为了研究一种新的脑扫描任务,以优化dlPFC功能横向化.
评估这项任务的可行性,以确定最佳的dlPFC对脑刺激的目标.

主要方法:

对58名参与者 (34名男性,24名女性) 的回顾性分析,使用涉及创造性解决问题,执行决策和工作记忆的任务.
神经学家和神经心理学家评估了成像数据,以确定主导手和dlPFC横向化.
参与者根据使用爱丁堡手性库存的手性进行了分类.

主要成果:

有很大比例的参与者表现出非传统的dlPFC横向化:21.4%的右撇子具有右半球优势,而16.7%的左撇子具有左半球优势.
该任务展示了作为一种有效方法来定位dlPFC目标的潜力.

结论:

开发的脑扫描任务显示了有效dlPFC功能横向化的前景.
需要进一步的研究来验证和扩展这些发现用于大脑刺激的临床应用.

关键词:

背侧侧前额皮质前额皮质功能性核磁共振成像 (MRI) 的使用.功能侧面化的功能侧面化.这是一种双手性.语言横向化 (lateralization) 是一种语言横向化.多模式的MRI.重复的跨脑磁性刺激是重复性的.基于任务的BOLD.

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